Neurocognitive Disorder (HAND) Neurocognitive
impairment (NCI) associated with HIV infection of brain
impacts a large proportion of people with HIV regardless of antiretroviral therapeutics
-1.2 Million in the US are HIV positive/30K new cases/year
-44%+ or 500K will develop Neurocognitive Disorders
-10.6% or 127K have moderate/severe cognitive
impairment.
Common Symptoms Decline in thinking, or "cognitive,"
functions such as memory, reasoning, judgment,
concentration, problem solving, personality, behavior,
speech, and motor (movement)
Currently there are no approved treatments f0r HAND and
new therapeutic alternatives are desperately needed.